Patrick Mahaffy is a renowned biopharmaceutical executive with a distinguished oncology-focused drug development and commercialization career in the United States and Europe. His extensive leadership experience and strategic insight have positioned him as a critical figure in the industry. Born and raised in Boulder, Colorado, Mr. Mahaffy now resides in South Florida, where he continues his passion for drug development.
His career journey has taken him from investment banking at Warburg Pincus (1986-1992) to CEO positions at multiple successful biotechnology firms. He first showcased his leadership skills at Nexstar Pharmaceuticals, which he led from 1992 to 1998 before its acquisition by Gilead Sciences. Under his guidance, Nexstar's primary drug, Ambisome, became the standard of care for certain life-threatening fungal infections.
Following Nexstar, he took the reins of Pharmion in 2000. He navigated the company through its acquisition by Celgene (now Bristol Myers Squibb) in 2008. Under his leadership, Pharmion's leading drug, Vidaza, became the standard for treating myelodysplastic syndrome and acute myeloid leukemia.
In 2009, he co-founded Clovis Oncology and served as its CEO. Clovis developed and marketed a drug for ovarian and prostate cancer in the US and Europe and initiated early-stage clinical development of targeted radionuclide therapy. Unfortunately, the company faced challenges due to the effects of COVID-19 on cancer diagnoses and FDA concerns regarding its drug class for ovarian cancer treatment. Clovis ceased operations in late 2022.
His academic pursuits include a Bachelor's degree in International Affairs from Lewis and Clark College and a Master’s in International Affairs from Columbia University.
Outside his professional life, he is known for his philanthropic contributions, particularly to family assistance funds. Despite his significant charitable work, he prefers to maintain a low profile in this regard. He also serves as a long-standing member of the Board of Trustees for Lewis & Clark College.
His impact on the industry stems from his strategic vision, collaborative leadership style, and relentless pursuit of knowledge. His rich experience in drug development and commercialization has led to the creation of drugs that remain the standard of care for their approved indications. He takes pride in establishing commercial organizations in the US and Europe for each company he has led.
Beyond his professional accomplishments, he is an enthusiastic sports fan, enjoying hiking, golf, and reading. His interest in archaeology was sparked when he discovered Clovis-age tools in his Colorado backyard in 2009. These artifacts, known as the Mahaffy Cache, are among a few Clovis-age caches in North America and are displayed at the University of Colorado History Museum. Although he leads a high-profile professional life, he keeps his personal life private, enjoying time with his family and friends.
Embarking on his professional journey, Patrick Mahaffy was associated with Warburg Pincus from 1986 to 1992. Here, he honed his skills as an investment banker, laying the foundation for his illustrious career ahead.
CEO of Clovis Oncology